Natural Antioxidant Boosts Therapeutic Potential Original Story Here University of Barcelona What began as research aimed at expanding the limited treatment options for cystinuria, a rare genetic disorder affecting one in every 7,000 people, characterized by the recurrent formation of cystine stones in the kidneys and urinary tract, could become a potential solution for millions [...]
It’s been a part of my life for 21 years Many who know me know that I live with Cystinuria. It’s been a part of my life for 21 years now. Over that time, I’ve gone through more surgeries, procedures, and doctor visits than I can count, and it still continues. Some days I [...]
How variant discovery redefines genetic prevalence: the case of cystine stone disease Original Story Here Abstract Cystine stones are caused by pathogenic variants in SLC3A1 or SLC7A9. Our prior study revealed a large gap between genetic and clinical prevalence. With increasing discovery of novel variants, we aim to assess how these impact genetic prevalence estimates. Due to the [...]
Cystinuria Treatment Market to Reach US$ 216.50 Million by 2030 at 4.80% CAGR; North America Leads with 40% Share - Key Players: Travere Therapeutics, Teva Pharmaceutical, Advicenne Original Story Here Cystinuria Treatment Market Overview The global cystinuria treatment market reached US$164.20 million in 2024 and is expected to reach US$216.50 million by 2030, growing at [...]
Tiopronin Safety in Cystinuria: First Real-World Pharmacovigilance Analysis Using the FDA Adverse Event Reporting System (FAERS): An EAU YAU and Endourology Sections Review - Beyond the Abstract Cystinuria is a lifelong hereditary disorder that begins in childhood and leads to recurrent cystine stone formation with a substantial risk of progressive renal damage. When conservative measures [...]
Partial correction of cystinuria type A in mice via kidney-targeted transposon delivery We used kidney-targeted, non-viral, transposon-mediated gene delivery to express the mouse Slc3a1 transgene in one kidney of cystinuria type A (Slc3a1−/−) mice. We found a 44% reduction in urinary cystine concentration at 154 days post-gene transfer, although there was no significant effect on cystine stone [...]
Non-viral gene therapy to treat cystinuria Aug. 4, 2025 Original Story (Unfortunately the story is buried behind a paywall so we may need to wait for the study to be published before we can see more.) In an effort to develop next-generation treatments for cystinuria, researchers at Vanderbilt University and Tennessee Valley Health Services have [...]
Cystinuria Pipeline Insight 2025: Redefining Treatment through Precision Therapies and Rare Disease Innovation | DelveInsight Original Story 07-21-2025 04:20 PM CET | Health & Medicine Press release from: DelveInsight DelveInsight's "Cystinuria - Pipeline Insight, 2025" provides a detailed examination of the ongoing therapeutic R&D landscape targeting cystinuria, a rare inherited disorder characterized by defective renal reabsorption of [...]
Cystinuria Awareness Day in Dixie! Holly C Hey! My name is Holly, and I am 41 years old, and am from Hanceville, AL. , about an hour north of Birmingham. I was diagnosed with Cystinuria at the age of 14, so it will be 27 years this fall since I was diagnosed. One [...]
My story and I’m still alive to tell it Brenda I had my first kidney stone when I was 17. I was at a slumber party, passed out, and woke up the next morning in terrible pain. They cut through my left side, from my belly to my back — and that was [...]
