Cystinuria in Pregnancy READ FULL STORY HERE When cystinuria leads to calculi, stones, getting stuck within the urinary tract, this results in pain in the flank, upper abdomen, or the back. Typically, the pain advances to the lower abdomen or the groin and you also may suffer from urinary urgency/frequency, nausea and vomiting, [...]
Ca2+-mediated higher-order assembly of heterodimers in amino acid transport system b0,+ biogenesis and cystinuria READ FULL STORY HERE Abstract Cystinuria is a genetic disorder characterized by overexcretion of dibasic amino acids and cystine, causing recurrent kidney stones and kidney failure. Mutations of the regulatory glycoprotein rBAT and the amino acid transporter b0,+AT, which [...]
Shedding light on the mechanisms of cystinuria Calcium ions tie cystine transporters for correct trafficking and function A team from the Max Planck Institute of Biophysics (Frankfurt am Main), The Jikei University School of Medicine (Tokyo) and Nara Medical University (Nara) in Japan explored the molecular mechanisms of a genetic disease called cystinuria [...]
Living life to the fullest despite having Cystinuria If you hear Sophie Popham talk about Cystinuria, you might not think kidney stones are all that painful. Not because kidney stones don’t cause excruciating pain, but because the outgoing, energetic 15-year-old, who was diagnosed with Cystinuria less than two years ago, is more excited about [...]
Living with Cystinuria for 44 years, and I'm one of the lucky ones Bruce Weisberg has lived with Cystinuria for 44 years, and he says he is one of the lucky ones. Although he has undergone four surgeries, with two of them in the last four years, he says this is nothing compared to [...]
The antiviral effects of thiol drugs in COVID-19 A recent study published in the American Journal of Physiology-Lung Cellular and Molecular Physiology investigated the effects of thiol drugs on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Background Coronavirus disease 2019 (COVID-19), caused by SARS-CoV-2, is a multidimensional disease characterized by pneumonia progressing to respiratory [...]
Living with cystinuria My name is Mandi Payne and I have been suffering from cystinura for 5 years. Throughout those years I have undergone around 20 surgeries and pain every single day. I want to share my story because education is one way to help find a cure. I have spent the almost all [...]
Meet Three Siblings Fighting Cystinuria Originally posted on Global Genes in 2012 Note: There is an update to this story HERE If you have ever had or known someone that had kidney stones, you may understand the excruciating pain associated with these monsters. The pain has been described as the worst, unbearable pain that you [...]
NOTE: This was a press release from DelveInsight. It looks like the main objective is to look at the potential for investing in companies that are associated with Cystinuria, but there is some great data here, so thought it was work posting. ====================== Cystinuria Market: Industry Analysis, Treatment, Pipeline Drugs and Key Companies By [...]
I was told I would likely need surgery every 6 - 12 months (Jen) I was diagnosed with Cystinuria at the age of 16 in my final year of high school. On diagnosis they had found that I had completely blocked off my left kidney and was turning septic, however after having surgery [...]
